Society for Translational Oncology Fellows' Forum (STOFF) is an intensive 3-day workshop, scheduled for Thursday, August 18 - Saturday, August 20, 2022, that brings together 25 fellows and junior faculty within 5 years of training completion from leading medical, surgical, radiation, and pediatric oncology groups and subspecialty fellowships to educate these rising stars on issues around and barriers to successful translational cancer research.

This forum is internationally acclaimed for its focused, practical, and personal approach. It provides guidance to oncology fellows and junior faculty regarding how to apply translational research findings in tumor biology to improve patient outcomes. The broad-based curriculum covers a range of topics related to new drug development.

With a faculty to student ratio of 1:1.5, trainees have unique opportunities to connect with other scientists and clinicians in translational research efforts that benefit from multidisciplinary and interprofessional investigation.

The faculty features prominent scientists, clinicians, ethicists, industry representatives, and biotech investors who serve as mentors. These distinguished leaders in cancer drug development lecture and lead discussions topics such as:

  • Preclinical and clinical evaluation
  • Validation of targets and biomarkers
  • Confirmation of mechanism of action and resistance in clinical trials
  • Racial and age-related disparities in clinical trials
  • Mechanics of grant-writing
  • Guidelines for good basic research

“Educating young oncologists in the field of clinical and translational research is an investment in the future and is likely to impact the quality of cancer patient care for years to come,” said Bruce A. Chabner (Massachusetts General Hospital/Harvard Medical School), founder the course more than two decades ago. Since then, many of the 540+ alumni have earned significant acclaim in their careers and drug development success.

After completion of this training, participants should be able to:

  • Identify the importance of translational research and define its value in clinical medicine.
  • Describe the process of drug development in oncology.
  • Apply the mechanics of grant writing and guidelines for sound research practices.
  • Establish a network of peer oncologists focused on translational research.

STOFF 2022 Agenda

Thursday, August 18, 2022
5:30–6:15pm Welcome Reception  
6:15–7:00pm Introductions and Dinner  
7:00–8:30pm Keynote Address: Oncology Drug Development: A Regulatory Perspective
Virtual Presentation
Tatiana Prowell, MD
Friday, August 19, 2022
7:00–8:15am Welcome and Course Objectives Keith Flaherty, MD and Ross Levine, MD
8:15–9:00am Career Development in Academia Bernardo H.L. Goulart, MD, MS
9:00–9:45am Science at the Interface Between the Lab and the Clinic Ryan Corcoran, MD, PhD
9:45-10:00am Coffee Break  
10:00–10:45am Systemic Toxicity Associated With Immune Checkpoint Inhibitors – More Questions than Answers
Virtual Presentation
Kerry Reynolds, MD
10:45–12:15pm Career Counseling for Lab-Based and Clinical Investigators Keith Flaherty, MD and Ross Levine, MD
12:15–1:30pm Lunch  
  ROUNDTABLE TOPIC 1 - Regulatory Issues Bernardo H.L. Goulart, MD, MS
  ROUNDTABLE TOPIC 2 - Overcoming Barriers in Career Development and Progressions Ross Levine, MD
1:30–2:15pm The Cost and Value of Cancer Medicine
Virtual Presentation
Thomas Roberts, MD
2:15–3:00pm Immune Checkpoint Antibodies from the Clinical Development Aspect Michael Postow, MD
3:00–3:45pm Networking/Mentoring  
Saturday, August 20, 2022
8:00–8:15am Welcome Back and Introductory Remarks Bruce Chabner, MD
8:15–9:00am Working with Industry in Drug Development Bruce Chabner, MD
9:00–9:45am Phase I/II Clinical Trials: Protocol (and Career) Development Keith Flaherty, MD
9:45-10:00am Coffee Break  
10:00–10:45am Issues in Design of Translational Research Trials Susan Hilsenbeck, PhD
10:45–11:30am IRB Issues and PI Responsibilities and Conflict of Interest
Virtual Presentation
Stacey Berg, MD
11:30am–12:15pm Therapeutic Resistance Including Serial Biopsy, Rapid Autopsy and Blood-based Biomarkers Platforms Dejan Juric, MD
12:15–2:00pm Lunch/Networking  
2:00pm Adjourn